If using NDs on the 5D2 to create shallow focus does not turn out to be a fool's errand (i.e., the camera laughs at you and still refuses to open up, changing the shutter speed and ISO instead just to watch how mad you get), filmmakers will be using them just like they do on any other motion-picture camera -- which is to say, a lot. Probably even more liberally than normal filmmakers do, as it may take 1.8 instead of .9 to persuade the 5D2 Exposure Dictator to give you something close to the aperture you are seeking.
(An Arri will stay at ASA 100 and 1/48 shutter speed no matter what. Putting on a 3-stop ND lets you open up exactly 3 stops. The Canon 5D2 is unlikely to be as cooperative.)
Infrared pollution is a problem associated with heavy ND use. The NDs block the visible spectrum but not the IR spectrum. In still photography, this becomes an issue mostly in specialized situations, as it's somewhat rare for a still shooter to resort to a really heavy ND to control light; increasing shutter speed makes more sense in most situations. When you're shooting movies with a fixed shutter speed, however, NDs are a routine fact of life for daylight shooting. If you want to knock that f/22 down to f/4, and you probably do if you want this to look like a movie instead of a video, you need an ND 1.8+ in front of the lens. IR problems generally are considered to start at ND .9. That's when the ratio of IR to regular light becomes high enough to overwhelm the internal IR filter, if any.
The RED One camera has IR issues. Result:
http://www.reduser.net/forum/showthread.php?t=9412There are solutions, none of them great.
Does anyone know what the past performance of Canon sensors has been with regard to IR
pollution? (I'd test it myself, but right now I only have an ND .6 that fits my Canon lenses.)